Esbriet (Pirfenidone)

Esbriet (Pirfenidone) is used for the treatment of a chronic lung condition called idiopathic pulmonary fibrosis. This medicine slows the progression of the disease and improves lung functioning. It is important to tell your doctor about all your medical conditions before starting Esbriet. You should avoid direct exposure to sunlight while taking Esbriet as it can make your skin sensitive to sunlight. Take medical help immediately if you notice some unwanted symptoms. Esbriet is available as capsules (267 mg) and tablets (267 mg and 801 mg). Select your dosage below to view brand and generic Esbriet costs and place your order. Save up to 80% on Esbriet price when you buy Esbriet online from our online pharmacy.

Esbriet

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Select your dosage:

Brand Choices

Brand Esbriet 267mg
Product of Turkey Turkey Flag Shipped from Mauritus
Prescription Required
Manufactured by Catalent Pharma
Brand Esbriet 801mg
Product of Turkey Turkey Flag Shipped from Mauritus
Prescription Required
Manufactured by Catalent Pharma

Generic Alternatives

Generic Equivalent to Esbriet 200mg
Product of India India Flag
Prescription Required
Manufactured by Cipla Limited
Generic Equivalent to Esbriet 400mg
Product of India India Flag
Prescription Required
Manufactured by Cipla Limited
Generic Equivalent to Esbriet 600mg
Product of India India Flag
Prescription Required
Manufactured by Cipla Limited
Generic equivalent to Esbriet 801mg
Product of India India Flag
Prescription Required
Manufactured by Sun Pharma

Brand Choices

Brand options for this medication aren't available currently.

Generic Alternatives

Generic Equivalent to Esbriet 200mg
Product of India India Flag
Prescription Required
Manufactured by Cipla Limited

Brand Choices

Brand Esbriet 267mg
Product of Turkey Turkey Flag
Prescription Required
Manufactured by Catalent Pharma

Generic Alternatives

Generic options for this medication aren't available currently.

Brand Choices

Brand options for this medication aren't available currently.

Generic Alternatives

Generic Equivalent to Esbriet 400mg
Product of India India Flag
Prescription Required
Manufactured by Cipla Limited

Brand Choices

Brand options for this medication aren't available currently.

Generic Alternatives

Generic Equivalent to Esbriet 600mg
Product of India India Flag
Prescription Required
Manufactured by Cipla Limited

Brand Choices

Brand Esbriet 801mg
Product of Turkey Turkey Flag
Prescription Required
Manufactured by Catalent Pharma

Generic Alternatives

Generic equivalent to Esbriet 801mg
Product of India India Flag
Prescription Required
Manufactured by Sun Pharma

FREQUENTLY ASKED QUESTIONS (FAQs):

What is Esbriet?

Esbriet contains the active ingredient pirfenidone and is used to treat idiopathic pulmonary fibrosis (IPF). IPF is a chronic lung disease that affects the normal functioning of the lungs to exchange gases such as oxygen with the blood. Esbriet helps to improve the functioning of the lungs by slowing the progression of the disease.

Benefits and Uses of Esbriet:

Esbriet is a prescription drug recommended by doctors to treat patients with idiopathic pulmonary fibrosis. IPF causes swelling, inflammation, and scarring of the lung. Over time, this scarring (fibrosis) causes the lungs to stiffen, affecting their functioning. This further leads to difficulty in breathing.

The exact mechanism of action of Esbriet is not known. However, it has been shown to reduce the production of collagen by fibroblasts and the secretion of inflammatory molecules. Thereby it reduces the inflammation, slows down the progression of the disease, and increases the survival of IPF patients.

How to take Esbriet?

Esbriet is usually taken orally at the same time each day. The doctor may recommend a low starting dose of Esbriet and gradually increase your dose.

  • First 7 days: 267 mg tablet 3 times a day

  • Day 8-14: Two 267 mg or one 534 mg tablet 3 times a day

  • Day 15 onwards: Three 267 mg tablets or one 801 mg tablet 3 times a day.

The tablet should be taken during or after a meal as it may reduce adverse drug effects such as nausea and dizziness. In case you miss a dose of Esbriet, take it with food as soon as possible. It is highly advised to not take 2 doses at the same time.

Side effects of Esbriet:

Patients taking Esbriet may experience some common side effects including:

  • Weakness and dizziness
  • Insomnia
  • Upper respiratory tract infections
  • Sinusitis
  • Loss of appetite
  • Headache
  • Weight loss

Esbriet may also cause some serious side effects, including:

  • Yellowing of your skin or eyes, dark urine, and abdominal pain (symptoms of liver problems)
  • Sensitivity to sunlight and skin rashes
  • Nausea, vomiting, diarrhea, and heartburn
  • Call your doctor right away if these symptoms get worse or do not go away.

Drug Interactions:

Sometimes taking more than two drugs can change drug action and may increase the risk of adverse effects. Tell your doctor before starting the treatment if you are taking any other medications including:

  • Antibiotics such as rifamycins, ciprofloxacin, and chloramphenicol
  • Antidepressants such as fluoxetine, paroxetine, and fluvoxamine
  • Anti-seizure medications such as phenytoin

Tell your doctor if you smoke or if you have recently stopped smoking as smoking decreases the blood level of this medication.

Safety Information:

  • Before you take Esbriet, tell your doctor if you have had any other medical conditions, particularly liver or kidney disease.

  • Completely avoid smoking while taking the medicine

  • Consult with the doctor before using Esbriet if you are pregnant, plan to become pregnant, or are a breastfeeding mother.

  • Avoid direct exposure to sunlight, tanning beds, and sunlamps.

  • Tell your doctor if you take marijuana or drink alcohol as they can make you dizzier.

References:

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