Onglyza (Saxagliptin)

Onglyza is a brand-name drug of Saxagliptin. This medicine is used to control blood sugar levels in people with type 2 diabetes. It also helps to reduce the risk of heart attacks and strokes. Before starting Onglyza, tell your doctor if you have kidney or heart problems, pancreatitis, and joint pain. Also, share the list of medicines you take including herbal supplements. Always follow the diet and exercise program for maximum benefits. Contact your doctor immediately, if you have abdominal pain, trouble breathing, skin allergies, or joint pain after taking Onglyza.

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Onglyza

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Brand Onglyza 2.5mg
Product of India India Flag
Prescription Required
Manufactured by Bristol Mayer Squibb
Brand Onglyza 5mg
Product of India India Flag
Prescription Required
Manufactured by Bristol Mayer Squibb
Brand Onglyza 5mg
Product of Turkey Turkey Flag
Prescription Required
Manufactured by AstraZeneca
Brand Onglyza 5mg
Product of Canada Canada Flag
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Manufactured by AstraZeneca

Generic Alternatives

Generic options for this medication aren't available currently.

Brand Choices

Brand Onglyza 2.5mg
Product of India India Flag
Prescription Required
Manufactured by Bristol Mayer Squibb

Generic Alternatives

Generic options for this medication aren't available currently.

Brand Choices

Brand Onglyza 5mg
Product of India India Flag
Prescription Required
Manufactured by Bristol Mayer Squibb
Brand Onglyza 5mg
Product of Turkey Turkey Flag
Prescription Required
Manufactured by AstraZeneca
Brand Onglyza 5mg
Product of Canada Canada Flag
Prescription Required
Manufactured by AstraZeneca

Generic Alternatives

Generic options for this medication aren't available currently.

FREQUENTLY ASKED QUESTIONS (FAQs):

What is Onglyza?

Onglyza is a prescription medicine used to lower blood sugar levels in people with type 2 diabetes. Onglyza is an antidiabetic medication that contains the active ingredient Saxagliptin. It works by increasing the release of the hormone insulin from the pancreas especially after a meal and reducing the release of hormone glucagon which makes the liver release too much sugar. Onglyza helps to manage morning blood sugar and after-meal blood sugar spike.

It is not approved for patients with type 1 diabetes or diabetic ketoacidosis.

Uses and Benefits of Onglyza

Onglyza is used along with a proper diet and exercise to lower blood sugar levels in people with Type 2 diabetes. Type 2 diabetes is a condition in which either the body cannot use insulin to move sugar from the blood into your cells, or the body cannot produce enough insulin.

Onglyza helps to control the high blood sugar in the patient. It also prevents the serious complications caused by diabetes such as kidney damage, eye damage, blindness, nerve problems, and loss of limbs. It also reduced the chances of a heart attack or stroke.

Side Effects of Onglyza

Patients taking Onglyza may experience some common side effects, including:

  • Upper respiratory tract infection

  • Urinary tract infection

  • Headache

Talk to your doctor immediately, if you notice some serious side effects after taking Onglyza, including:

  • Inflammation of the pancreas and severe pain in the abdomen
  • Weight gain, tiredness
  • Shortness of breath or trouble breathing
  • Peripheral edema with symptoms such as swelling of hands, feet, or ankles and fluid retention
  • Low blood sugar with symptoms such as shaking, hunger, sweating, headache, rapid heartbeat, and vision change
  • Severe joint pain
  • Severe skin reaction (bullous pemphigoid), hives, rash, blisters, and the breakdown of the outer skin layer.

How to take Onglyza?

Onglyza comes in the form of tablets in two different strengths: 2.5 mg and 5 mg. Onglyza is taken orally with or without food once daily as prescribed by your doctor. Patients should not chew, crush or break the tablet. They are advised to swallow the tablet as a whole. Take Onglyza tablets at the same time each day to get maximum benefits.

In case you miss a dose of Onglyza, take it as soon as possible. And if it is time for the next dose, skip the missed dose and take the next dose at the regular time. People taking Onglyza should also follow the diet and exercise program recommended by the doctors. Always remember to check the blood sugar levels regularly.

Drug Interactions

Some drugs can interact with Onglyza and affect how well the medicine controls your blood sugar or can cause serious side effects. Tell your doctor if you use any of the following medications:

  • Beta-blockers such as metoprolol, propranolol, and glaucoma eye drops

  • Medications to lower blood sugar such as sulfonylurea and insulin

  • Diuretics

  • Antibiotics, antifungals, or HIV/AIDS medications

Safety Information

  • Do not take Onglyza if you are allergic to any of its ingredients.

  • Before starting the medication, tell your doctor if you have had kidney problems, pancreatitis, gallstones, high triglyceride levels, heart failure, joint pain, skin reactions, and a history of alcoholism.

  • Talk to your doctor about the safety of Onglyza if you are pregnant, breastfeeding, or plan to become pregnant or breastfeeding.

  • Contact your healthcare provider if you have fever, trauma, or infection as your doctor needs to change the medication dose.

  • Do not consume too much alcohol while taking Onglyza, as it can decrease the blood sugar level and increase the risk of pancreatitis.

Reference:

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